no-reflow phenomenon


no-reflow phenomenon

 [no re´flo] when cerebral blood flow is restored following prolonged global cerebral ischemia, there is initial hyperemia followed by a gradual decline in perfusion until there is almost no blood flow.

no-reflow phenomenon

Cardiology The finding that restoration of antegrade flow in an occluded epicardial artery in acute MI may not result in recovery of microvascular tissue perfusion; Pts with NRP have lower
1-month ejection fractions, larger end-diastolic volumes, and more persistent heart failure; Pts at high risk with significant zones of no reflow after thrombolytics might need emergency coronary angiography, and benefit from early and aggressive ACE inhibition to prevent LV remodeling. See Ventricular remodeling.