NME

Abbreviation for:
National Medical Enterprises
necrolytic migratory erythema
neuromuscular efficiency
North, Midlands and East (Programme for IT)

erythema

(er?i-the'ma ) [Gr. erythema, redness] Reddening of the skin. Erythema is a common but nonspecific sign of skin irritation, injury, or inflammation. It is caused by dilation of superficial blood vessels in the skin. erythematicerythematous (er?i-the-mat'ik) (er?i-them'at-us), adjective

erythema ab igne

Localized erythema due to exposure to heat. Synonym: toasted skin syndrome.

ERYTHEMA ANNULARE

erythema annulare

A red, ring-shaped rash. See: illustration

erythema cenicienta

Erythema dyschromicum perstans.

erythema chronicum migrans

Abbreviation: ECM
Erythema migrans.

erythema dyschromicum perstans

Awaiting Don's def. Synonym: ashy dermatosis; erythema cenicienta

erythema elevatum diutinum

A form of vasculitis that affects the skin on the extensor surfaces of the forearms or legs. Iit is often seen in those infected with HIV.

erythema induratum

Chronic vasculitis of the skin occurring in young women. Hard cutaneous nodules break down to form necrotic ulcers and leave atrophic scars. Synonym: Bazin disease

erythema infectiosum

A mild, moderately contagious disease seen most commonly in school-age children. Synonym: fifth disease

Etiology

The causative agent is human parvovirus B-19. Transmission is thought to be via respiratory secretions from infected patients; however, maternal-fetal transmission can occur and hemolytic disease of the newborn may result.

Symptoms

Patients experience a mild, brief illness; complaints include fever, malaise, headache, and pruritus. The characteristic erythema appears about 10 days later. Facial redness is similar to that which occurs when a child is slapped; however, circumoral redness is absent. Several days following initial erythema, a less distinct rash may appear on the extremities and trunk. The rash usually resolves within 1 week but may occur for several weeks when the patient is exposed to heat, cold, exercise, or stress. Adults may also experience arthralgia and arthritis although these symptoms are less common in children. In addition, mild transient anemia, thrombocytopenia, and leukopenia may develop.

Treatment

Most patients require no specific therapy. Patients with chronic hemolytic anemia may experience transient aplastic crisis (TAC). These patients should be warned of the danger of exposure to parvovirus B-19 infection, informed of the early signs and symptoms, and instructed to seek medical consultation promptly if exposure is suspected. Patients with TAC may develop a life-threatening anemia that requires immediate blood transfusion or partial exchange transfusion.

erythema intertrigo

Chafing.

linear gingival erythema

A band of inflammation of the periodontium, appearing as a reddish gingival band about 2 to 3 mm in width. It is often associated with HIV/AIDS. Synonym: red band gingivitis

erythema marginatum

A form of erythema multiforme in which the center of the area fades, leaving elevated edges.

erythema migrans

Abbreviation: EM
The hallmark of acute infection with Lyme disease. EM is an expanding red rash with a sharply defined border and (typically) central clearing. The rash usually appears within 3–32 days after a tick bite. The center of the rash is the site of inoculation. The causative agent is Borrelia burgdorferi, a spirochete that may later invade the joints, the central nervous system, or the conducting system of the heart. Synonym: erythema chronicum migrans See: Lyme disease for illus

ERYTHEMA MULTIFORME

erythema multiforme

Abbreviation: EM
A rash usually caused by an immune response to drugs or to an infection, esp. herpes simplex virus. It may express itself on the skin in multiform ways, including macules, papules, blisters, hives, and, characteristically, iris or target lesions. It may involve the palms and soles, the mucous membranes, the face, and the extremities. The disease is usually self-limited. The most severe (and occasionally fatal) variant of the illness, in which the eyes, mouth, and internal organs are involved, is called Stevens-Johnson syndrome, or toxic epidermal necrolysis. Synonym: Hebra disease (1.) See: illustration

necrolytic migratory erythema

Abbreviation: NME
Red, blistering or crusting patches that appear on the skin of the buttocks, groin, lower extremities, or perineum. The lesions are itchy and painful. NME is often associated with glucagonomas.

erythema nodosum

A tender, red, nodular rash on the shins that typically arises in conjunction with another illness, e.g., such as a streptococcal, fungal, or tubercular infection; inflammatory bowel disease; occult cancer; or sarcoidosis. Biopsies of the rash reveal inflammation of subcutaneous fat (panniculitis). Because the disease is often associated with other serious illnesses, a diagnostic search for an underlying cause usually is undertaken. In some patients, no cause is identified.

Treatment

Therapy is directed at the cause, when it is known. Nonsteroidal anti-inflammatory drugs provide symptomatic relief for many patients.

erythema nodosum leprosum

Abbreviation: ENL
A red, nodular vasculitic rash, which may be a complication of the treatment for leprosy. See: lepra

Treatment

Treatment consists of withdrawing therapy against leprosy (clofazimine, steroids, thalidomide).

punctate erythema

Erythema occurring in minute points, such as scarlet fever rash.

toxic erythema

Redness of the skin or a rash resulting from toxic agents such as drugs.

erythema toxicum neonatorum

A benign, self-limited rash marked by firm, yellow-white papules or pustules from 1 to 2 mm in size present in about 50% of full-term infants. The cause is unknown, and the lesions disappear without need for treatment.

erythema venenatum

Erythema caused by contact with a toxic substance.

necrolytic migratory erythema

new molecular entity

NME

A unique, pharmacologically active product that has never previously been synthesized or used to treat disease.