ossification center


ossification center

[TA] the site of earliest bone formation via accumulation of osteoblasts within connective tissue (membranous ossification) or of earliest destruction of cartilage before onset of ossification (endochondral ossification). Synonym(s): centrum ossificationis [TA], center of ossification, ossific center, point of ossification, punctum ossificationis

ossification center

The site or sites in bones where calcification begins and bone replaces fibrous connective tissue or cartilage. The region of bone formation at the center of the body of a long bone is called the primary (diaphyseal) ossification center. Most secondary ossification centers are found in the epiphyses. See also: center