MAP2K2
MAP2K2
A gene on chromosome 19p13.3 that encodes mitogen-activated protein kinase kinase 2, which catalyses the simultaneous phosphorylation of a threonine and a tyrosine residue in MAP kinases; it also activates the ERK1 and ERK2 MAP kinases.Molecular pathology
Defects of MAP2K2 cause cardiofaciocutaneous syndrome.