nucleoside reverse transcriptase inhibitor

n. Abbr. NRTI Any of a group of antiviral drugs, such as stavudine, that interfere with the activity of the enzyme reverse transcriptase, are structural analogs of natural nucleosides, and are used chiefly to treat HIV infection.

Thesaurus

Noun

nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugsNRTIAZT, Retrovir, ZDV, zidovudine - an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrowdrug cocktail, HAART, highly active antiretroviral therapy - a combination of protease inhibitors taken with reverse transcriptase inhibitors; used in treating AIDS and HIV3TC, lamivudine - a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIVreverse transcriptase inhibitor - an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV

Abbreviation: NRTI
Any of a class of antiretroviral drugs used to treat patients with HIV infection. NRTIs prevent transcription of viral RNA to host DNA by interfering with the action of the enzyme reverse transcriptase. Zidovudine, dideoxyinosine, zalcitabine, d4T, and abacavir are NRTIs. See: reverse transcriptase inhibitorSee also: inhibitor

nucleoside reverse transcriptase inhibitor