释义 |
MEF2D MEF2D A gene on chromosome 1q12-q23 that encodes a transcriptional activator that binds specifically to the MEF2 element on various muscle-specific, growth factor- and stress-induced genes. MEF2D mediates cellular functions in skeletal and cardiac muscle development, in neuronal differentiation and survival, and in control of cell growth, survival and apoptosis via p38 MAPK signalling in muscle-specific and/or growth factor-related transcription. |