megaloblastic madness

megaloblastic madness

A popular term for the neurologic changes of vitamin B12 deficiency—e.g., altered personality, dementia, spastic weakness, and ataxia—due to demyelination of lateral and posterior columns of spinal cord.

megaloblastic madness

Neurology The neurologic changes of vitamin B12 deficiency–eg, altered personality, dementia, spastic weakness, ataxia, due to demyelination of lateral and posterior columns of spinal cord. See Subacute combined degeneration.