leukotriene receptor antagonists

leukotriene receptor antagonists

drugs that block the binding of leukotrienes to cysteinyl leukotriene T1 receptors, thus inactivating the action of leukotrienes.
See also: antileukotriene.

leukotriene receptor antagonists

Drugs that prevent the action of LEUKOTRIENES by blocking their receptors on cell membranes, such as those of smooth muscle. These drugs have a useful dual effect in relaxing the smooth muscle of the air passages (bronchi) and in combatting inflammation in the bronchial linings-both features of ASTHMA. They have also been found useful in hay fever. Examples are montelukast (Singulair) and zafirlukast (Accolate).