monocyte

enUK

mon·o·cyte

M0392800 (mŏn′ə-sīt′)n. A large white blood cell that circulates in the blood and then migrates into the tissues, where it matures into a macrophage. Monocytes have a single well-defined nucleus.

mon′o·cyt′ic (-sĭt′ĭk), mon′o·cy′toid′ (-sī′toid′) adj.

monocyte

(ˈmɒnəʊˌsaɪt) n (Physiology) a large phagocytic leucocyte with a spherical nucleus and clear cytoplasm monocytic adj ˌmonoˈcytoid adj

mon•o•cyte

(ˈmɒn əˌsaɪt)

n. a large white blood cell that is formed in bone marrow and spleen and circulates in the blood and may enter tissue to become a macrophage. [< German Monozyt (1910); see mono-, -cyte] mon`o•cyt′ic (-ˈsɪt ɪk) adj. mon`o•cy′toid, adj.

mon·o·cyte

(mŏn′ə-sīt′) Any of various large white blood cells that circulate in the blood and mature into macrophages. Monocytes engulf and break down microorganisms capable of causing infection.

Thesaurus

Noun

monocyte - a type of granular leukocyte that functions in the ingestion of bacterialeucocyte, leukocyte, WBC, white blood cell, white blood corpuscle, white cell, white corpuscle - blood cells that engulf and digest bacteria and fungi; an important part of the body's defense systemmonoblast - a large immature monocyte normally found in bone marrow

Translations

monocyte

enUK

monocyte

[mon´o-sīt] a mononuclear, phagocytic leukocyte, 13 μm to 25 μm in diameter, having an ovoid or kidney-shaped nucleus and azurophilic cytoplasmic granules. Monocytes are derived from promonocytes in the bone marrow and circulate in the blood for about 24 hours before migrating to the tissues, such as the lung and liver, where they develop into macrophages. adj., adj monocyt´ic.

mon·o·cyte

(mon'ō-sīt), A relatively large mononuclear leukocyte (16-22 mcm in diameter) that normally constitutes 3-7% of the leukocytes of the circulating blood and is normally found in lymph nodes, spleen, bone marrow, and loose connective tissue. When treated with the usual dyes, monocytes manifest an abundant pale blue or blue-gray cytoplasm that contains numerous fine, dustlike, red-blue granules; vacuoles are frequently present; the nucleus is usually indented, or slightly folded, and has a stringy chromatin structure that seems more condensed where the delicate strands are in contact. Monocytes that leave the bloodstream and enter the connective tissue spaces are called macrophages.
See also: monocytoid cell, endothelial leukocyte. [mono- + G. kytos, cell]

monocyte

(mŏn′ə-sīt′)n. A large, circulating, phagocytic white blood cell, having a single well-defined nucleus and very fine granulation in the cytoplasm. Monocytes constitute from 3 to 8 percent of the white blood cells in humans.

mon′o·cyt′ic (-sĭt′ĭk), mon′o·cy′toid′ (-sī′toid′) adj.

monocyte

Hematology A phagocytic WBC that arises in BM from a common progenitor, CFU-GM; 'daughter' monocytes circulate in the blood, forming resident and transient populations in various sites; resident monocytes–histiocytes include Kupffer cells–liver, Langerhans cells–dermis, microglial cells–brain, pleural, peritoneal, alveolar macrophages and osteoclasts; monocytes normally constitute 2%–8% of peripheral WMCs, measure 12-25 µm, have a reniform nucleus with lacy chromatin, an N:C ratio of 4:1 to 2:1, and gray blue cytoplasm containing lysosomal enzymes–eg, acid phos, arginase, cathepsins, collagenases, deoxyribonuclease, lipases, glycosidases, plasminogen activator and others, and surface receptors–eg, FcIgG and C3R; monocytes are less efficient in phagocytosis than PMNs, but have a critical role in antigen processing. See CFU-GM, White blood cell.

mon·o·cyte

(mon'ō-sīt) A relatively large mononuclear leukocyte (16-22 mcm in diameter); monocytes normally constitute 3-7% of the leukocytes of the circulating blood; normally found in lymph nodes, spleen, bone marrow, and loose connective tissue. In stained smears, monocytes have abundant pale blue or blue-gray cytoplasm that contains numerous fine red-blue granules and vacuoles; the nucleus is usually indented, or slightly folded. [mono- + G. kytos, cell]

MONOCYTES: (Orig. mag. ×640)

monocyte

(mon'o-sit?) [ mono- + -cyte],

MO

A mononuclear phagocytic white blood cell derived from myeloid stem cells. Monocytes circulate in the bloodstream for about 24 hr and then move into tissues, at which point they mature into macrophages, which are long lived. Monocytes and macrophages are one of the first lines of defense in the inflammatory process. This network of fixed and mobile phagocytes that engulf foreign antigens and cell debris previously was called the reticuloendothelial system and is now referred to as the mononuclear phagocyte system (MPS). See: illustration; blood for illus.; macrophagemonocytic (mon-o-sit'ik), adjectiveillustration

monocyte

A large white blood cell with a round or kidney-shaped nucleus. There are no granules in the CYTOPLASM. The monocyte migrates to the tissues where it becomes a MACROPHAGE.

monocyte

macrocyte

a type of LEUCOCYTE (white blood cell) of the AGRANULOCYTE group that is produced from stem cells in the bone marrow and is 12–15 μm in diameter. Monocytes remain in the blood for a short time and then migrate to other tissues as MACROPHAGES, moving particularly to those areas invaded by bacteria and other foreign materials where they ingest large particles by PHAGOCYTOSIS. See also HISTOCYTE, LYMPHOCYTE.

Monocyte

White blood cell that increases during a variety of conditions including severe infections. It removes debris and microorganisms by phagocytosis.Mentioned in: AIDS, AIDS Tests, White Blood Cell Count and Differential

mon·o·cyte

(mon'ō-sīt) A relatively large mononuclear leukocyte that normally constitutes 3-7% of the leukocytes in circulating blood. [mono- + G. kytos, cell]

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Words related to monocyte

noun a type of granular leukocyte that functions in the ingestion of bacteria

Related Words