biotin
enUKbi·o·tin
B0270600 (bī′ə-tĭn)biotin
(ˈbaɪətɪn)bi•o•tin
(ˈbaɪ ə tɪn)n.
bi·o·tin
(bī′ə-tĭn)Noun | 1. | biotin - a B vitamin that aids in body growth |
单词 | biotin | |||
释义 | biotinenUKbi·o·tinB0270600 (bī′ə-tĭn)biotin(ˈbaɪətɪn)bi•o•tin(ˈbaɪ ə tɪn)n. bi·o·tin(bī′ə-tĭn)
biotinenUKbiotin:see vitaminvitamin,group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes. ..... Click the link for more information. ; coenzymecoenzyme , any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in ..... Click the link for more information. . BiotinA vitamin, widespread in nature. It is only sparingly soluble in water; it is stable in boiling water solutions, but can be destroyed by oxidizing agents, acids, and alkalies. Under some conditions, it can be destroyed by oxidation in the presence of rancid fats. Biotin's occurrence in nature is so widespread that it is difficult to prepare a natural deficient diet. Biotin deficiency in animals is associated with dermatitis, loss of hair, muscle incoordination and paralysis, and reproductive disturbances. Biotin deficiency produced in humans by feeding large amounts of egg white resulted in dermatitis, nausea, depression, muscle pains, anemia, and a large increase in serum cholesterol. See Coenzyme Biotin(vitamin H), a water-soluble vitamin contained in yeasts and other microorganisms, and also in liver, egg yolk, kidneys, milk, cauliflower, and other vegetable products. The daily requirement of humans for biotin (0.25 mg) is usually provided by the microflora of the intestinal tract; it is therefore unnecessary to introduce it in the diet. Biotin has been obtained synthetically. Avitaminosis H may be produced in laboratory animals by feeding large quantities of raw egg white, which contains a biotin antagonist, avidin, which decomposes when heated to 100° C. Affection of the skin of the seborrheic type is observed in avitaminosis H. Biotin is a coenzyme and participates in the transfer of carbon dioxide gas and its fixation in biosynthesis; its other functions have not been clarified. biotin[′bī·ə·tən]biotinbiotinenUKbiotin[bi´o-tin]bi·o·tin(bī'ō-tin),See also: avidin. biotin(bī′ə-tĭn)biotinA water-soluble B vitamin.Biochemistry Biotin is the d-isomer of vitamin-B2 complex, which is a prosthetic group for carboxylase enzymes and important in fatty acid biosynthesis and catabolism. It is present in and essential for most animals, as it participates in carboxylation; daily requirements are in the mg range; biotin deficiency is rare. Lab medicine Biotin is widely used as a covalent label for macromolecules which are detected by high-affinity binding of labelled avidin or streptavidin. Molecular biology Biotin can be incorporated into dUTP and used as a non-radioactive label for a DNA probe. It is used to label nucleic acids and proteins that may be subsequently detected by avidin or streptavidin linked to a fluorescent or enzymatic reporter molecule. bi·o·tin(bī'ō-tin)biotinA water-soluble B vitamin concerned in the metabolism of fats and carbohydrates. Deficiency causes DERMATITIS, muscle pain, loss of appetite and ANAEMIA.biotina water-soluble vitamin of the B-COMPLEX present in many foods, including yeast, liver and fresh vegetables. Biotin acts as a COENZYME in amino acid and lipid METABOLISM. A deficiency (rare in humans) of biotin causes dermatitis and intestinal problems.bi·o·tin(bī'ō-tin)See also: avidin biotinenUK
Synonyms for biotin
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