| 单词 | biphosphonate |
| 释义 | biphosphonatebiphosphonateEndocrinology Any of a number of carbon-substituted analogues of pyrophosphate, an endogenous inhibitor of bone mineralization Indications Malignant hypercalcemia, Paget's disease, breast and prostate CA, myeloma; the most potent is zoledronic acid, which can be given at intervals of up to one yr Adverse events Oral–GI intolerance; IV–myalgia, pyrexia. See Osteoporosis. |
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