释义 |
natural killer cell
natural killer celln. A large granular lymphocyte that kills virus-infected, cancerous, or abnormal cells without first having been exposed to specific antigens and that also produces a variety of cytokines. Also called NK cell.nat′ural kill′er cell` n. a small killer cell that destroys virus-infected cells or tumor cells without activation by an immune system cell or antibody. Compare killer T cell. natural killer cell
natural killer cell[¦nach·rəl ′kil·ər ‚sel] (histology) A large, granular lymphocyte that can lyse a variety of target cells when it is activated by interferon. Abbreviated NK. natural killer cell
natural killer celln. A lymphocyte that is activated by double-stranded RNA or lymphokines and fights off viral infections and tumors without evident antigenic specificity. Also called NK cell.natural killer cell Abbreviation: NK cell A large granular lymphocyte – a defensive cell of innate immunity – that bonds to cells and lyses them by releasing cytotoxins. Natural killer cells are null cells, lymphocytes that do not have B cell or T cell surface markers, and they can be activated without previous antigen exposure. NK cells destroy cells infected with viruses and some types of tumor cells in cultures. They also secrete gamma interferon (INF?), tumor necrosis factor alpha (TNFa), and granulocyte-macrophage colony-stimulating factor (GMCSF), enhancing the effect of T lymphocytes. Synonym: killer cellSee also: cellNatural killer (NK) cellA lymphocyte that acts as a primary immune defense against infection.Mentioned in: Chronic Fatigue SyndromeLegalSeeCellFinancialSeecellAcronymsSeeNKC |