Leyden-Möbius muscular dystrophy


limb-·gir·dle mus·cu·lar dys·tro·phy

[MIM*253600] a group of muscular dystrophies, probably heterogeneous in nature. Onset usually in childhood or early adulthood and both sexes affected. Characterized by weakness and wasting, usually symmetric, of the pelvic girdle muscles, the shoulder girdle muscles, or both, but not the facial muscles. Muscle pseudohypertrophy, heart involvement, and mental retardation are absent. Autosomal dominant and recessive inheritance have been described. Synonym(s): Leyden-Möbius muscular dystrophy, pelvofemoral muscular dystrophy, scapulohumeral muscular dystrophy

Leyden-Möbius muscular dystrophy

(1) Limb-girdle muscular dystrophy, see there. 
(2) Juvenile spinal muscular atrophy, see there; also known as Kugelberg-Welander syndrome.

Leyden,

Ernst V. von, German physician, 1832-1910. Charcot-Leyden crystals - see under CharcotLeyden ataxia - Synonym(s): Westphal-Leyden syndromeLeyden crystals - Synonym(s): Charcot-Leyden crystalsLeyden diseaseLeyden-Möbius muscular dystrophy - Synonym(s): limb-girdle muscular dystrophyLeyden neuritis - fatty degeneration of the fibers of the affected nerve.Westphal-Leyden syndrome - see under Westphal

Möbius,

Paul J., German physician, 1853-1907. Leyden-Möbius muscular dystrophy - Synonym(s): limb-girdle muscular dystrophyMöbius sign - impairment of ocular convergence in Graves disease.Möbius I syndrome - moderate migraine accompanied by extraocular palsy. Synonym(s): occasional oculomotor paralysis; ophthalmoplegic migraineMöbius II syndrome - a developmental bilateral facial paralysis usualy associated with oculomotor or other neurological disorders.Synonym(s): congenital facial diplegia; developmental bilateral facial paralysis