Leydig cell hyperplasia

Leydig cell hyperplasia

A condition characterised by diffuse autonomous hyperfunction of hyperplastic Leydig cells.
 
Aetiology
Activating mutation of LHCGR, the luteinising hormone receptor gene.
 
Clinical findings
Precocious puberty.
 
Management
Orchidectomy.

Leydig cell hyperplasia

Endocrinology Autonomous hyperplasia and hyperfunction of Leydig cells Etiology Activating mutation of LH receptor gene Clinical Precocious puberty Management Orchidectomy