marimastat


marimastat

A matrix metalloproteinase and angiogenesis inhibitor which had shown early promise for managing advanced malignancy; phase-III studies failed in this expectation, however. Marimastat may have a secondary role as maintenance therapy for advanced colorectal, ovarian, pancreas, prostate and other cancers.
 
Adverse effects
Musculoskeletal pain.

marimastat

Oncology An angiogenesis inhibitor and matrix metalloproteinase inhibitor in clinical trials as an ancillary therapy for advanced malignancy–ovary, pancreas, small cell of lung, stomach, glioblastoma. See Angiogenesis inhibitors.