释义 |
DictionarySeemenEncyclopediaSeeneoplasiamultiple endocrine neoplasia
neoplasia [ne″o-pla´zhah] the formation of a neoplasm.cervical intraepithelial neoplasia (CIN) dysplasia of the cervical epithelium, often premalignant, characterized by various degrees of hyperplasia, abnormal keratinization, and the presence of condylomata.multiple endocrine neoplasia (MEN) a group of rare hereditary disorders of autonomous hyperfunction of more than one endocrine gland. In Type I (MEN I), called also Wermer's syndrome, there are tumors of the pituitary, parathyroid gland, and pancreatic islet cells in association with a high incidence of peptic ulcer. Type II (MEN II), called also Sipple's syndrome, is characterized by medullary carcinoma of the thyroid, pheochromocytoma, often bilateral and multiple, and parathyroid hyperplasia. Type III (MEN III), called also mucosal neuroma syndrome, resembles Type II except that parathyroid hyperplasia is rare, the mean survival time is shorter, and there may be neuromas and neurofibromas. All forms are transmitted as autosomal dominant traits.multiple endocrine neoplasia (MEN), a group of disorders characterized by functioning tumors in more than one endocrine gland. Synonym(s): familial multiple endocrine adenomatosis, multiple endocrine adenomatosismultiple endocrine neoplasia See MEN. mul·ti·ple en·do·crine ne·o·pla·si·a (MEN) (mŭlti-pĕl endō-krin nēō-plāzē-ă) A group of disorders characterized by functioning tumors in more than one endocrine gland. Multiple endocrine neoplasiaAbnormal tissue growth on one or more of the endocrine (hormone-secreting) glands.Mentioned in: Follicle-Stimulating Hormone Testmul·ti·ple en·do·crine ne·o·pla·si·a(MEN) (mŭlti-pĕl endō-krin nēō-plāzē-ă) Group of disorders characterized by functioning tumors in more than one endocrine gland. AcronymsSeeMEN |