KRT16

KRT16

A gene on chromosome 17q21.2 that encodes a type-I keratin, an intermediate filament protein that provides the structural integrity of epithelial cells. KRT16 may be co-expressed with KRT14 in the oesophagus, tongue and hair follicles.
Molecular pathology
KRT16 mutations are associated with pachyonychia congenita type 1, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.