KRT4

KRT4

A gene on chromosome 12q13.13 that encodes a type-II cytokeratin that is specifically co-expressed in differentiated layers of mucosal and oesophageal epithelia with family member KRT13.
Molecular pathology
KRT4 mutations are associated with white sponge nevus, which is characterised by oral, oesophageal and anal leukoplakia.