lichen sclerosis

lichen sclerosis

Gynecology A pruritic mucosal lesion which is more common in older, often post-menopausal white ♀, that may have a vague genetic component in a background of autoimmunity; the cutaneous lesions consist of flat-topped coalescing white macules; LS evolves towards malignancy in 5% of ♂, but it is not premalignant in ♀