mini-chromosome

(1) An artificial chromosome created by linking restriction endonuclease digested fragments of DNA.
(2) An extremely small chromosome composed of centromeres and telomeres, in contrast to a conventional chromosome, which also has a large amount of introns (intervening DNA).
New genes can be stacked onto mini-chromosomes, making it much easier to move the genes to target sites, in contrast to traditional genetic modification in which genes are incorporated into a vector and difficult to manipulate.

单词	mini-chromosome
释义	mini-chromosome mini-chromosome (1) An artificial chromosome created by linking restriction endonuclease digested fragments of DNA. (2) An extremely small chromosome composed of centromeres and telomeres, in contrast to a conventional chromosome, which also has a large amount of introns (intervening DNA). New genes can be stacked onto mini-chromosomes, making it much easier to move the genes to target sites, in contrast to traditional genetic modification in which genes are incorporated into a vector and difficult to manipulate.
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