bcl-1

CCND1

A gene on chromosome 11q13 that encodes a member of the highly conserved cyclin family, which regulates CDK kinases. Cyclin D1 forms a complex with and is a regulatory subunit of CDK4 or CDK6, which are required for cell cycle G1/S transition; it also interacts with tumour suppressor protein Rb, which regulates the expression of CCND1.

Molecular pathology
CCND1 mutations, amplification and overexpression alter cell cycle progression, occur in various tumours and play a role in tumourigenesis.

bcl-1

Proto-ONCOGENEs concerned with the persistence of LYMPHOCYTES. Mutations can cause various kinds of lymphocytic lymphomas and chronic lymphocytic leukaemia. bcl-1 genes are situated at chromocoam sites that break easily.

单词	bcl-1
释义	bcl-1 CCND1 A gene on chromosome 11q13 that encodes a member of the highly conserved cyclin family, which regulates CDK kinases. Cyclin D1 forms a complex with and is a regulatory subunit of CDK4 or CDK6, which are required for cell cycle G1/S transition; it also interacts with tumour suppressor protein Rb, which regulates the expression of CCND1. Molecular pathology CCND1 mutations, amplification and overexpression alter cell cycle progression, occur in various tumours and play a role in tumourigenesis. bcl-1 Proto-ONCOGENEs concerned with the persistence of LYMPHOCYTES. Mutations can cause various kinds of lymphocytic lymphomas and chronic lymphocytic leukaemia. bcl-1 genes are situated at chromocoam sites that break easily.
随便看	hcsds hcse hcsecu hcseg hcsel hcsez hcsf hcsg hc shepardson hcshg hcsi hcsia hcsif hcsig hcsin hcsis hcsit hcsj hcsk hcsl hcsm hcsma hcsmc hcsmf hcsnv