lung transplant

lung transplant

Surgery Transplant of a lung allograft into a Pt with failing lungs; 90 US centers perform LT; 35 centers perform ≥ 10/yr Mean wait time 18 months Indications COPD–eg, emphysema due to α1-AT deficiency, cystic fibrosis–CF, bronchiectasis, emphysema, Eisenmenger syndrome, end-stage heart disease Immunosuppression Cyclosporine, tacrolimus, azathioprine, mycophenolate mofetil, prednisone Prognosis 1/3/5 yrs–71%/55%/43% Cost $240,000, $47,000 annual maintenance. See Cyclosporin, Domino-donor transplantation, Tacrolimus, UNOS.