odontogenic keratocyst


o·don·to·gen·ic ke·ra·to·cyst

a cyst of dental lamina origin with a high recurrence rate and well-defined histologic criteria of a corrugated parakeratin surface, uniformly thin epithelium, and a palisaded basal layer. One manifestation of the basal cell nevus syndrome.

keratocystic odontogenic tumour

A benign cystic lesion of the jaw—75% in mandible, 90% behind canines—which arises in the dental lamina, often associated with impacted teeth; average age, 41 years; male:female ratio, 2:1. If multiple tumours are seen, basal cell nevus syndrome (a condition accompanied by basal cell carcinoma, ovarian fibroma, palmar pits, and medulloblastoma) should be excluded.
Management
KCOTs notoriously recur; initial surgery should include a generous margin and a rim of uninvolved bone.

o·don·to·gen·ic ker·a·to·cyst

(ō-don'tō-jen'ik ker'ă-tō-sist) A cyst originating in the dental lamina that has a high recurrence rate, a corrugated parakeratin surface, uniformly thin epithelium, and a palisaded basal layer; one manifestation of the basal cell nevus syndrome.

o·don·to·gen·ic ker·a·to·cyst

(ō-don'tō-jen'ik ker'ă-tō-sist) Lesion of dental lamina origin with a high recurrence rate and well-defined histologic criteria of corrugated parakeratin surface, uniformly thin epithelium, and a palisaded basal layer. One manifestation of the basal cell nevus syndrome.