nick translation


nick trans·la·tion

a technique in which a bacterial DNA polymerase is used to degrade a single strand of DNA that has been nicked and then to resynthesize that strand, often with labeled nucleoside triphosphates.

nick translation

a process of repairing a NICK in a DNA MOLECULE using the enzyme DNA POLYMERASE. This method is often used in vitro to introduce labelled NUCLEOTIDES into DNA in order to label a DNA PROBE.