| 释义 |
DictionarySeestrandlagging strand
lagging strand[′lag·iŋ ‚strand] (cell and molecular biology) In deoxyribonucleic acid (DNA) replication, the 3′ to 5′ DNA strand that is discontinuously synthesized as a series of Okazaki fragments in the 5′ to 3′ direction. lagging strand
lagging strand In DNA replication, the single strand forming a duplex in the direction away from the fork in the parental DNA. Replication on the lagging strand is discontinuous and can occur briefly in both directions.lagging strand the strand in DNA replication that is synthesized discontinuously, to generate Okazaki fragments (named after R. Okazaki who first detected them). These are later sealed by DNA LIGASE. See DNA, SEMICONSERVATIVE REPLICATION MODEL. |