lyonization

[li″on-ĭ-za´shun] the process by which or the condition in which all X chromosomes of the cells in excess of one are inactivated on a random basis.

ly·on·i·za·tion

(lī'on-i-zā'shŭn), The normal phenomenon that wherever there are two or more haploid sets of X-linked genes in each cell all but one of the genes are inactivated apparently at random and have no phenotypic expression. Lyonization is usual but not invariable for all loci. Its randomness explains the more variable espressivity of X-linked traits in women than in men. Lyonization occurs in men with the Klinefelter (XXY) karyotype.
See also: gene dosage compensation. Synonym(s): Lyon hypothesis, X inactivation, X-inactivation [M. Lyon]

lyonization

Genetics A normal genetic event that consists of inactivation of all X chromosomes–portions of the 'inactivated' chromosome may remain functional if in excess of one

ly·on·i·za·tion

(lī'on-ī-zā'shŭn) The normal phenomenon whereby wherever there are two or more haploid sets of X-linked genes in each cell, all but one of the genes are inactivated apparently at random and have no phenotypic expression. Its randomness explains the more variable expressivity of X-linked traits in women than in men.
See also: gene dosage compensation
Synonym(s): Lyon hypothesis, X-inactivation. [M. Lyon]

Lyonization

See X-INACTIVATION.

Lyon,

Mary F., English cytogeneticist, 1925–. Lyon hypothesis - Synonym(s): lyonizationlyonization - the normal phenomenon that wherever there are two or more haploid sets of X-linked genes in each cell, all but one of the genes are inactivated, apparently at random, and have no phenotypic expression. Synonym(s): Lyon hypothesis; X-inactivation

单词	lyonization
释义	EncyclopediaSeeLyon hypothesis lyonization lyonization [li″on-ĭ-za´shun] the process by which or the condition in which all X chromosomes of the cells in excess of one are inactivated on a random basis. ly·on·i·za·tion (lī'on-i-zā'shŭn), The normal phenomenon that wherever there are two or more haploid sets of X-linked genes in each cell all but one of the genes are inactivated apparently at random and have no phenotypic expression. Lyonization is usual but not invariable for all loci. Its randomness explains the more variable espressivity of X-linked traits in women than in men. Lyonization occurs in men with the Klinefelter (XXY) karyotype. See also: gene dosage compensation. Synonym(s): Lyon hypothesis, X inactivation, X-inactivation [M. Lyon] lyonization Genetics A normal genetic event that consists of inactivation of all X chromosomes–portions of the 'inactivated' chromosome may remain functional if in excess of one ly·on·i·za·tion (lī'on-ī-zā'shŭn) The normal phenomenon whereby wherever there are two or more haploid sets of X-linked genes in each cell, all but one of the genes are inactivated apparently at random and have no phenotypic expression. Its randomness explains the more variable expressivity of X-linked traits in women than in men. See also: gene dosage compensation Synonym(s): Lyon hypothesis, X-inactivation. [M. Lyon] Lyonization See X-INACTIVATION. Lyon, Mary F., English cytogeneticist, 1925–. Lyon hypothesis - Synonym(s): lyonizationlyonization - the normal phenomenon that wherever there are two or more haploid sets of X-linked genes in each cell, all but one of the genes are inactivated, apparently at random, and have no phenotypic expression. Synonym(s): Lyon hypothesis; X-inactivation
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