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osteomalacia
os·te·o·ma·la·cia O0142800 (ŏs′tē-ō-mə-lā′shə, -shē-ə)n. A bone disease in adults analogous to rickets in children, marked by bone demineralization caused by impaired metabolism or deficiency of vitamin D or phosphorus.
[New Latin : osteo- + Greek malakiā, softness (from malakos, soft; see mel- in Indo-European roots).]osteomalacia (ˌɒstɪəʊməˈleɪʃɪə) n (Pathology) a disease in adults characterized by softening of the bones, resulting from a deficiency of vitamin D and of calcium and phosphorus[C19: from New Latin, from osteo- + Greek malakia softness] ˌosteomaˈlacial, osteomalacic adjos•te•o•ma•la•cia (ˌɒs ti oʊ məˈleɪ ʃə, -ʃi ə)
n. a condition characterized by softening of the bones with resultant pain, weakness, and bone fragility. [1815–25] os`te•o•ma•la′cial, adj. osteomalaciasoftening of the bones resulting from malnutrition and the consequent loss of essential salts from the bones.See also: BonesosteomalaciaA group of disorders caused by lack of vitamin D. With insufficient minerals, bones soften and weaken. Weightbearing bones may bend or fracture.Thesaurus| Noun | 1. | osteomalacia - abnormal softening of bones caused by deficiencies of phosphorus or calcium or vitamin Dmalacia - a state of abnormal softening of tissuedemineralisation, demineralization - abnormal loss of mineral salts (especially from bone) |
TranslationsOsteomalacia
osteomalacia[¦äs·tē·ō·mə′lā·shə] (medicine) Failure of bone to ossify due to a reduced amount of available calcium. Also known as adult rickets. Osteomalacia a bone disease that is manifested by softening and deformity of bone as a result of disturbances in mineral metabolism; usually, the depletion of calcium salts, phosphoric acid, and vitamin D is the cause. Osteomalacia generally occurs in women, especially during pregnancy, in which case the pelvic bones and adjacent portions of the skeleton are particularly affected. Recovery occurs in the postpartum period. Bones may remain permanently deformed after osteomalacia as a result of calcification. REFERENCE“Osteomaliatsiia.” In Bol’shaia meditsinskaia entsiklopediia, 2nd ed., vol. 22, Moscow, 1961.
In animals. Osteomalacia in animals is manifested clinically by a decreased and unusual appetite, during which the animal exhibits pica and eats inedible objects. Other symptoms are emaciation and lowered productivity, lameness, loose teeth, sluggishness, curvature or sagging of the spinal column, and bone fractures. The diagnosis is based on analysis of the mineral and vitamin D content of feed; the calcium, phosphorus, and phosphatase content of blood; and roentgenograms of the tail vertebrae. Osteomalacia in animals is prevented by exercise, by regular checks of the feed and inclusion of optimum quantities of minerals and vitamins, and by ultraviolet irradiation while the animals are in their stalls.REFERENCEVnutrennie nezaraznye bolezni zhivotnykh. Edited by A. M. Kolesov. Leningrad, 1972.osteomalacia
osteomalacia [os″te-o-mah-la´shah] softening of the bones, resulting from impaired mineralization, with excess accumulation of osteoid, caused by a vitamin D deficiency in adults. A similar condition in children is called rickets. The deficiency may be due to lack of exposure to ultraviolet rays, inadequate intake of vitamin D in the diet, or failure to absorb or utilize vitamin D. There is decalcification of the bones, particularly those of the spine, pelvis, and lower extremities. X-ray examination reveals transverse, fracture-like lines in the affected bones and areas of demineralization in the matrix of the bone. As the bones soften they become bent, flattened, or otherwise deformed. Treatment consists of administration of large daily doses of vitamin D and dietary measures to insure adequate calcium and phosphorus intake. adj., adj osteomala´cic.antacid-induced osteomalacia osteomalacia in which the combination of low dietary phosphorus intake and chronic excessive consumption of aluminum hydroxide–containing antacids has led to phosphate depletion; characteristics include hypophosphatemia, nephrolithiasis, anorexia, muscle weakness, and bone loss.anticonvulsant osteomalacia 1. osteomalacia occurring in rickets" >anticonvulsant rickets of children.2. rickets" >anticonvulsant rickets in adults.hepatic osteomalacia osteomalacia as a complication of cholestatic liver disease, which may lead to severe bone pain and multiple fractures.oncogenic osteomalacia a type seen in association with usually benign mesenchymal neoplasms. The tumors appear to produce a substance that impairs renal tubular functions and leads to hypophosphatemia. Called also tumor-induced osteomalacia.puerperal osteomalacia a type resulting from exhaustion of skeletal stores of calcium and phosphorus by repeated pregnancies and lactation.renal tubular osteomalacia a type resulting from acidosis and hypercalciuria when deficient renal tubular activity has caused inability to produce acid urine or ammonia.senile osteomalacia softening of bones in old age due to vitamin D deficiency.tumor-induced osteomalacia oncogenic osteomalacia.os·te·o·ma·la·ci·a (os'tē-ō-mă-lā'shē-ă), A disease in adults characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue that has failed to calcify because of lack of vitamin D or renal tubular dysfunction; more common in women than in men, osteomalacia often begins during pregnancy. Synonym(s): adult rickets, late rickets, rachitis tarda [osteo- + G. malakia, softness] osteomalacia (ŏs′tē-ō-mə-lā′shə, -shē-ə)n. A bone disease in adults analogous to rickets in children, marked by bone demineralization caused by impaired metabolism or deficiency of vitamin D or phosphorus.osteomalacia Nutritional rickets A condition characterized by softened bones due to poor mineralization occurring in a background of vitamin D deficiency Clinical Weak, deformed, and deformable bone, which in children may be manifest by craniotabes, bowlegs, and knock knees, rachitic rosary, ↓ ventilation, often accompanied by pneumonia, muscular weakness, ↓ appetite, hypocalcemia Treatment Vitamin D. See Osteogenic osteomalacia, Rickets. os·te·o·ma·la·ci·a (os'tē-ō-mă-lā'shē-ă) A disease characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue which has failed to calcify due to lack of vitamin D or renal tubular dysfunction.
Synonym(s): adult rickets, late rickets. [osteo- + G. malakia, softness]osteomalacia Bone softening as a result of defective mineralization, usually occurring because of defective calcium absorption from vitamin D deficiency. Osteomalacia is commoner in women than in men. The softened bones may distort or bend under the body weight. The condition is treated with vitamin D.OsteomalaciaOsteomalacia is a bone disease that occurs in adults and is caused by a prolonged period of vitamin D deficiency.Mentioned in: Bone X Rays, Laxatives, Vitamin D Deficiencyos·te·o·ma·la·ci·a (os'tē-ō-mă-lā'shē-ă) Disease in adults characterized by a gradual softening and bending of bones with varying severity of pain.
Synonym(s): adult rickets. [osteo- + G. malakia, softness]osteomalacia
Related to osteomalacia: Paget's diseaseWords related to osteomalacianoun abnormal softening of bones caused by deficiencies of phosphorus or calcium or vitamin DRelated Words- malacia
- demineralisation
- demineralization
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