lyophilization

ly·oph·i·lize

L0308200 (lī-ŏf′ə-līz′)tr.v. ly·oph·i·lized, ly·oph·i·liz·ing, ly·oph·i·liz·es To freeze-dry (blood plasma or other biological substances).

[lyophil(ic) + -ize.]

ly·oph′i·li·za′tion (-lĭ-zā′shən) n.ly·oph′i·liz′er n.

lyophilization

(laɪˌɒfɪlaɪˈzeɪʃən) or

lyophilisation

n (Biology) the act of lyophilizing or freeze-drying (blood, serum, tissue, etc)

lyophilization

a process for preserving substances such as blood or serum by freeze-drying in a high vacuum.See also: Cold, Processes

Thesaurus

Noun

lyophilization - a method of drying food or blood plasma or pharmaceuticals or tissue without destroying their physical structure; material is frozen and then warmed in a vacuum so that the ice sublimesfreeze-drying, lyophilisationdrying up, evaporation, desiccation, dehydration - the process of extracting moisturefreeze, freezing - the withdrawal of heat to change something from a liquid to a solid

Translations

lyophilisation

Lyophilization

enUK

lyophilization

[lī‚äf·ə·lə′zā·shən] (chemical engineering) Rapid freezing of a material, especially biological specimens for preservation, at a very low temperature followed by rapid dehydration by sublimation in a high vacuum.

Lyophilization

freeze-drying, the drying of biological objects in a frozen state under vacuum, the water being removed by sublimation of the ice (that is, conversion to steam, bypassing the liquid phase).

Lyophilization makes it possible to obtain dry tissues, medical preparations, and food products without a loss of structural integrity and biological activity. Most proteins are not denatured by the process and can be stored for a long time afterward under moderate cold (about 0°C). Freeze-dried tissues and preparations regain their initial properties when wetted. The process is used when there is a need for the long-term storage and preservation of various products of biological origin; to obtain dry donor plasma and dry sera and vaccines; for organ and tissue transplants; and in the pharmaceuticals and food industries. In the life-support systems of spaceships, it may be used as a means of regenerating water from moisture-containing materials.

REFERENCE

Primenenie zamorazhivaniia-vysushivaniia ν biologii. Edited by R. Harris. Moscow, 1956. (Translated from English.)

lyophilization

[li-of″ĭ-lĭ-za´shun] the creation of a stable preparation of a biologic substance by rapid freezing and dehydration of the frozen product under high vacuum. See also freeze-drying.

ly·oph·i·li·za·tion

(lī-of'i-li-zā'shŭn), 1. The process of isolating a solid substance from solution by freezing the solution and evaporating the ice under vacuum. 2. The process of imparting lyophilic properties to a substance. Synonym(s): freeze-drying

lyophilization

Freeze drying A method for preserving foods or biologicals, where a substance–eg, coagulation factor VIII, is 'snap-frozen' in liquid nitrogen–-70ºC and placed in a high vacuum to remove the water vapor as it sublimes; once the water is removed, the substance is brought to room temperature and stored. Cf Quick-freeze technique.

ly·oph·i·li·za·tion

(lī-of'i-lī-zā'shŭn) The process of isolating a solid substance from solution by freezing the solution and evaporating the ice under vacuum.
Synonym(s): freeze-drying.

lyophilization

see FREEZE-DRYING.

lyophilization

ly·oph·i·lize

lyophilization

lyophilisation

lyophilization

Lyophilization

lyophilization

Lyophilization

REFERENCE

lyophilization

lyophilization

ly·oph·i·li·za·tion

lyophilization

ly·oph·i·li·za·tion

lyophilization

lyophilization

Synonyms for lyophilization

noun a method of drying food or blood plasma or pharmaceuticals or tissue without destroying their physical structure

Synonyms

Related Words