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neuroleptic
neu·ro·lep·tic N0071750 (no͝or′ə-lĕp′tĭk, nyo͝or′-)n. An antipsychotic or anesthetic drug that causes apathy and decreased affect.
[French neuroleptique : neuro-, nerve (from Greek; see neuro-) + -leptique, affecting (from Greek lēptikos, seizing, from lēptos, seized, from lambanein, lēp-, to seize, take).]
neu′ro·lep′tic adj.neuroleptic (ˌnjʊərəʊˈlɛptɪk) adj (Pharmacology) capable of affecting the brain, esp by reducing the intensity of nerve function; tranquillizingn (Pharmacology) a neuroleptic drug; major tranquillizer, used in the treatment of psychosesan•ti•psy•chot•ic (ˌæn ti saɪˈkɒt ɪk, ˌæn taɪ-)
adj. 1. of or pertaining to any of various drugs used in the treatment of psychosis, esp. schizophrenia, and severe states of mania, depression, or paranoia. n. 2. Also called neuroleptic. an antipsychotic drug. [1950–55] Thesaurus| Noun | 1. |  neuroleptic - tranquilizer used to treat psychotic conditions when a calming effect is desiredantipsychotic, antipsychotic agent, antipsychotic drug, major tranquilizer, major tranquilliser, major tranquillizer, neuroleptic agent, neuroleptic drugchlorpromazine, Thorazine - a drug (trade name Thorazine) derived from phenothiazine that has antipsychotic effects and is used as a sedative and tranquilizerclozapine, Clozaril - an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effectsdiphenylbutyl piperidine - a group of antipsychotic drugs used mainly in the treatment of schizophreniafluphenazine - tranquilizer used to treat psychotic disordersHaldol, haloperidol - tranquilizer (trade name Haldol) used to treat some psychotic disorders and Tourette's syndromeloxapine, Loxitane - a tranquilizer (trade name Loxitane) used to treat schizophreniaMoban, molindone - antipsychotic drug (trade name Moban) used in the treatment of schizophreniaprochlorperazine - antipsychotic and antiemetic drug used to treat schizophrenia and to combat nausea and vomitingMellaril, thioridazine - a tranquilizer (trade name Mellaril) used to treat schizophrenia and other psychotic disordersNavane, thiothixene - a tranquilizer (trade name Navane) used to treat schizophreniaantianxiety agent, ataractic, ataractic agent, ataractic drug, tranquilizer, tranquilliser, tranquillizer - a drug used to reduce stress or tension without reducing mental clarityEskalith, Lithane, lithium carbonate, Lithonate - a white powder (LiCO3) used in manufacturing glass and ceramics and as a drug; the drug (trade names Lithane or Lithonate or Eskalith) is used to treat some forms of depression and manic episodes of manic-depressive disorder |
Translationsneuroleptic
neuroleptic[‚nu̇r·ō′lep·tik] (pharmacology) A drug that is useful in the treatment of mental disorders, especially psychoses. Pertaining to the actions of such a drug. neuroleptic
neuroleptic [noor″o-lep´tik] a term coined to refer to the effects on cognition and behavior of the original antipsychotic agents, which produced a state of apathy, lack of initiative, and limited range of emotion and in psychotic patients caused a reduction in confusion and agitation and normalization of psychomotor activity. The term is still used to refer to agents, such as droperidol, used to produce such effects as part of anesthesia or analgesia; however, it is outdated as a synonym for antipsychotic agents because newer agents do not necessarily have such effects.neuroleptic malignant syndrome a rare but dramatic condition that occurs in severely ill patients being treated with high-potency antipsychotics (neuroleptics); symptoms include diaphoresis, muscle rigidity, and hyperpyrexia. It is believed to be caused by dopamine blockade in the hypothalamus.neu·ro·lep·tic (nū'rō-lep'tik), Any of a class of psychotropic drugs used to treat psychosis, particularly schizophrenia; includes the phenothiazine, thioxanthene, and butyrophenone derivates and the dihydroindolones. Synonym(s): neuroleptic agent
See also: antipsychotic agent. [neuro- + G. lēpsis, taking hold] neuroleptic (no͝or′ə-lĕp′tĭk, nyo͝or′-)n. An antipsychotic or anesthetic drug that causes apathy and decreased affect.
neu′ro·lep′tic adj.antipsychotic adjective Referring to an antipsychotic drug.
noun Any drug that attenuates psychotic episodes.
Agents
Phenothiazines, thioxanthenes, butyrophenones, dibenzoxazepines, dibenzodiazepines, diphenylbutylpiperidines.
Main types of antipsychotics
Typical and atypical, which differ in their side/adverse effects.
Indications
Management of schizophrenic, paranoid, schizo-affective and other psychotic disorders; acute delirium, dementia, manic episodes (during induction of lithium therapy), control of movement disorders (in Huntington’s disease), Tourette syndrome, ballismus, intractable hiccups, severe nausea and vomiting (by blocking the medulla’s chemoreceptor trigger zone).
Adverse effects
Extrapyramidal effects (dystonia, akathisia, parkinsonism), tardive dyskinesia due to blocking of basal ganglia; sedation and autonomic side effects (orthostatic hypotension, blurred vision, dry mouth, nasal congestion and constipation) are due to blocking of histaminic, cholinergic and adrenergic receptors.neuroleptic Psychiatry An agent used to treat psychotic illnesses–eg, obsessive-compulsive disorderneu·ro·lep·tic (nūr'ō-lep'tik) 1. Any of a class of psychotropic drugs used to treat psychosis, particularly schizophrenia; includes the phenothiazine, thioxanthene, and butyrophenone derivatives and the dihydroindolones.
See also: antipsychotic agent
Synonym(s): neuroleptic agent. 2. Denoting a condition similar to that produced by such an agent. [neuro- + G. lēpsis, taking hold]neuroleptic 1. Capable of bringing about emotional quietening without impairing consciousness. Capable of modifying abnormal psychotic behaviour. 2. Any drug having these effects. NeurolepticAnother name for older antipsychotic medications, such as haloperidol. The term does not apply to such newer atypical agents as clozapine (Clozaril).Mentioned in: Personality Disorders, Schizophrenianeuroleptic
Related to neuroleptic: Neuroleptic drugsSynonyms for neurolepticnoun tranquilizer used to treat psychotic conditions when a calming effect is desiredSynonyms- antipsychotic
- antipsychotic agent
- antipsychotic drug
- major tranquilizer
- major tranquilliser
- major tranquillizer
- neuroleptic agent
- neuroleptic drug
Related Words- chlorpromazine
- Thorazine
- clozapine
- Clozaril
- diphenylbutyl piperidine
- fluphenazine
- Haldol
- haloperidol
- loxapine
- Loxitane
- Moban
- molindone
- prochlorperazine
- Mellaril
- thioridazine
- Navane
- thiothixene
- antianxiety agent
- ataractic
- ataractic agent
- ataractic drug
- tranquilizer
- tranquilliser
- tranquillizer
- Eskalith
- Lithane
- lithium carbonate
- Lithonate
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