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DictionarySeemetachromaticMetachromasia
metachromasia[‚med‚ə·krō′mā·zhə] (chemistry) The property exhibited by certain pure dyestuffs, chiefly basic dyes, of coloring certain tissue elements in a different color, usually of a shorter wavelength absorption maximum, than most other tissue elements. The assumption of different colors or shades by different substances when stained by the same dye. Also known as metachromatism. Metachromasia in biology, the property of cells and tissues that causes them to take on a color that differs from that of a dye. For example, in staining with thiazine dyes, the basic matter of connective tissue, tumor cells, and certain other cells are stained not blue or violet, the color of the dye, but red or pink. It is thought that metachromasia is caused by the polymerization of the dye molecules under the influence of free negative charges in the tissue. metachromasia
metachromasia [met″ah-kro-ma´zhah] 1. failure to stain true with a given stain.2. the different coloration of different tissues produced by the same stain.3. change of color produced by staining. adj., adj metachromat´ic.met·a·chro·ma·si·a (met'ă-krō-mā'zē-ă), 1. The condition in which a cell or tissue component takes on a color different from the dye solution with which it is stained. Synonym(s): metachromatism (2) 2. A change in the characteristic color of certain basic thiazine dyes, such as toluidine blue, when the dye molecules are bound in proximate array to tissue polyanionic polymers, such as glycosaminoglycans. [meta- + G. chrōma, color] metachromasia The property of a tissue, due to the presence of sulfated polysaccharides and sialic acid mucins, which causes it to stain differently from the surrounding structures and from the colours used in the dye.met·a·chro·ma·si·a (met'ă-krō-mā'zē-ă) 1. The condition in which a cell or tissue component takes on a color different from the dye solution with which it is stained. Synonym(s): metachromatism (2) . 2. A change in the characteristic color of certain basic thiazine dyes, such as toluidine blue, when the dye molecules are bound to tissue polyanionic polymers. [meta- + G. chrōma, color]metachromasia The variations in colour produced in different parts of a tissue when stained with a single dye. |