metalloenzyme


metalloenzyme

 [mĕ-tal″o-en´zīm] any enzyme containing tightly bound metal atoms, e.g., the cytochromes.

me·tal·lo·en·zyme

(mĕ-tal'ō-en'zīm), An enzyme containing a metal (ion) as an integral part of its active structure, for example, cytochromes (Fe, Cu), aldehyde oxidase (Mo), catechol oxidase (Cu), carbonic anhydrase (Zn).

metalloenzyme

An enzyme that contains a metal ion, usually held by co-ordinate-covalent bonds on the amino acid side chains, or bound to a prosthetic group (e.g., heme). The metal ions function like coenzymes, imparting activity to the enzymes.
Examples
Alcohol dehydrogenase (zinc), ascorbic acid oxidase (copper), cytochrome (iron), cytochrome oxidase (copper), glutamate mutase (cobalt), glutathione peroxidase (selenium), urease (nickel), and xanthine oxidase (molybdenum).

me·tal·lo·en·zyme

(mĕ-tal'ō-en'zīm) An enzyme containing a metal (ion) as an integral part of its active structure; e.g., cytochromes (Fe, Cu), aldehyde oxidase (Mo), catechol oxidase (Cu), carbonic anhydrase (Zn).