neurosyphilis
neurosyphilis
(ˌnjʊərəʊˈsɪfɪlɪs)Noun | 1. | neurosyphilis - syphilis of the central nervous system |
单词 | neurosyphilis | |||
释义 | neurosyphilisneurosyphilis(ˌnjʊərəʊˈsɪfɪlɪs)
neurosyphilisneurosyphilis[¦nu̇r·ō′sif·ə·ləs]neurosyphilisneurosyphilis[noor″o-sif´ĭ-lis]neu·ro·syph·i·lis(nū'rō-sif'i-lis),neurosyphilisAny of the rare neurological manifestations of tertiary syphilis.Clinical findings Lightning-like pain, ataxia, optic nerve degeneration leading to blindness, urinary incontinence, loss of position sense, neuropathic arthropathy (Charcot joints), personality changes, aphasia, paralysis, seizures. Patients with early syphilis who are co-infected with HIV may not respond to high-dose penicillin G, leading to an increase in Tertiary syphilis. Clinical forms of neurosyphilis • Asymptomatic with only a positive VDRL in the CSF. • General paresis or chronic meningoencephalitis. • Gummatous. • Meningovascular or thromboembolic with cerebral infarction or cranial nerve defects. • Tabes with degeneration of the posterior columns of the spinal cord and nerve roots, decreased peripheral reflexes and proprioceptive sensation, evoking Charcot’s joints. neurosyphilisNeurology Any of the rare neural changes of 3º syphilis Clinical Lightning-like pain, ataxia, optic nerve degeneration → blindness, urinary incontinence, loss of position sense, Charcot's joints, personality changes, aphasia, paralysis, seizures. See STS-RPR, VDRL. See Charcot's joints, Windswept cortex, Tabes dorsalis. Cf Quaternary syphilis.neu·ro·syph·i·lis(nūr'ō-sif'i-lis)neurosyphilisAny syphilitic infection of the nervous system. This is usually a late (tertiary) manifestation of untreated SYPHILIS, but may occur in adolescence. Its effects are widespread and include TABES DORSALIS, general paralysis of the insane (general paresis or GPI), dementia and involvement of the blood vessels of the brain and the brain coverings (meningovascular syphilis).neurosyphilis
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