lipoamide

li·po·ic ac·id

(li-pō'ik as'id), A bacterial growth factor present in yeast and liver extracts; may be useful in the treatment of mushroom poisoning. Functions as the amide (lipoamide) cofactor in the disulfide (-S-S-) form in the transfer of "active aldehyde" (acetyl), the two-carbon fragment resulting from decarboxylation of pyruvate from α-hydroxyethylthiamin pyrophosphate to acetyl-CoA, itself being reduced to the dithiol form (that is, dihydrolipoic acid) in the process. Lipoic acid is also an essential component of other α-keto acid dehydrogenase complexes. Synonym(s): acetate replacement factor, ovoprotogen, protogen, protogen A, pyruvate oxidation factor, thioctic acid

单词	lipoamide
释义	DictionarySeelipoic acid lipoamide li·po·ic ac·id (li-pō'ik as'id), A bacterial growth factor present in yeast and liver extracts; may be useful in the treatment of mushroom poisoning. Functions as the amide (lipoamide) cofactor in the disulfide (-S-S-) form in the transfer of "active aldehyde" (acetyl), the two-carbon fragment resulting from decarboxylation of pyruvate from α-hydroxyethylthiamin pyrophosphate to acetyl-CoA, itself being reduced to the dithiol form (that is, dihydrolipoic acid) in the process. Lipoic acid is also an essential component of other α-keto acid dehydrogenase complexes. Synonym(s): acetate replacement factor, ovoprotogen, protogen, protogen A, pyruvate oxidation factor, thioctic acid
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