lipotoxicity

The pathologic changes in organs resultant from elevated fat levels in blood or tissues, as in the diabetic liver.

lipotoxicity

(lip″ŏ-tok-sis′ĭt-ē) [ lipo- + toxicity] The adverse effects on glucose metabolism of excessive concentrations of free fatty acids in the blood. These effects include an increase in the resistance of the liver and muscle to the effects of insulin, an increase in glucose production, and reductions in insulin secretion by the pancreas.

单词	lipotoxicity
释义	lipotoxicity lipotoxicity The pathologic changes in organs resultant from elevated fat levels in blood or tissues, as in the diabetic liver. lipotoxicity (lip″ŏ-tok-sis′ĭt-ē) [ lipo- + toxicity] The adverse effects on glucose metabolism of excessive concentrations of free fatty acids in the blood. These effects include an increase in the resistance of the liver and muscle to the effects of insulin, an increase in glucose production, and reductions in insulin secretion by the pancreas.
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