macroamylase

macroamylase

 [mak″ro-am´ĭ-lās] a complex in which normal serum amylase is bound to a variety of specific binding proteins, forming a complex too large for renal excretion. It is not correlated with any specific disease state; however, in hyperamylasemia or pancreatitis, it can result in urinary amylase levels not rising concomitantly with serum levels.

mac·ro·am·y·lase

(mak'rō-am'i-lās), Descriptive term applied to a form of serum amylase in which the enzyme is present as a complex joined to a globulin; the molecular weight of the enzyme itself is 50,000, whereas that of the complex probably exceeds 160,000; hence, renal excretion of the complex is not appreciable.

macroamylase

A high-molecular-weight (200-kD) plasma amylase, usually of salivary type, that circulates complexed to various large plasma proteins, such as IgG, IgA, polysaccharides, glycoproteins and alpha1-antitrypsin.

mac·ro·am·y·lase

(mak'rō-am'i-lās) A form of serum amylase in which the enzyme is joined to a globulin.