macrophage migration inhibitory factor

A 25-kD proinflammatory lymphokine, produced by T cells in response to antigenic stimulus, which inhibits macrophage migration.
Gene
MMIF is encoded by MIF on chromosome 22q11.23.
Activities
Cell-mediated immunity, inflammation and regulation of macrophage function in host defence by suppressing the anti-inflammatory effects of glucocorticoids.

Mechanism
Increases intracellular cAMP, polymerises microtubules, stops macrophage progression.

单词	macrophage migration inhibitory factor
释义	DictionarySeeGIFEncyclopediaSeeMIF macrophage migration inhibitory factor macrophage migration inhibitory factor A 25-kD proinflammatory lymphokine, produced by T cells in response to antigenic stimulus, which inhibits macrophage migration. Gene MMIF is encoded by MIF on chromosome 22q11.23. Activities Cell-mediated immunity, inflammation and regulation of macrophage function in host defence by suppressing the anti-inflammatory effects of glucocorticoids. Mechanism Increases intracellular cAMP, polymerises microtubules, stops macrophage progression. AcronymsSeeMMIF
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