macrophagic myofasciitis

macrophagic myofasciitis

A recently-described apparently new disease featuring fever, muscle and joint pain, muscle and general weakness and infiltration of the tissues around the muscles by sheets of large, finely-granular MACROPHAGES. The muscle fibres, themselves are minimally affected. The microscopic appearances are unlike those of any previous muscle or fascial disorder. The condition appears to respond to treatment with various combinations of antibiotics and steroids. It was first described by the French physicians and histopathologists Professor R.K. Gerardi, M. Coquet, F-J Authier, P. Laforêt,L. Bélec, D. Figarelle-Branger, J-M Mussini, J-F Pellissier and M. Fardeau.