单词 | matrix-assisted laser desorption ionisation |
释义 | matrix-assisted laser desorption ionisationmatrix-assisted laser desorption ionisationA process in mass spectrometry in which sample molecules are mixed with an excess of an energy-absorbing matrix and co-crystallised in a thin film on an inert metal support. Repeated irradiation of the film with a pulsed laser releases ions from the surface, which can be accelerated into a time-of-flight mass spectrometer. Because the matrix is usually a solid organic acid, the predominant mode of ionisation is protonation of the sample molecule M to form M H. |
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