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maduromycosis[¦maj·ə·rō‚mī′kō·səs] (medicine) mycetoma Maduromycosis (Madura foot, mycetoma), a chronic fungal disease (mycosis) affecting chiefly the feet and considerably more rarely other parts of the body. Gill of Madura (India) recognized the disease as a separate nosological unit (hence the name) in 1842. Maduromycosis is observed most often in tropical countries but is also found in Western Europe, and a few cases have been reported in the USSR. Infection usually occurs through a wound. At first reddish violet nodules of various sizes appear; subsequently they soften and open to the exterior through fistulas, from which pus containing yellow, black, and red granules is discharged. Later the foot becomes severely de-formed owing to destructive and reactive changes in the bone tissue. The disease may continue for dozens of years. Treatment includes surgical excision of primary foci and prescription of sulfanilamide preparations, streptomycin, and other drugs. In advanced states the foot may be amputated. maduromycosis
mycetoma [mi″sĕ-to´mah] an initially localized, slowly progressive, destructive infection of the cutaneous and subcutaneous tissues, fascia, and bone, caused by certain actinomycetes" >actinomycetes (actinomycotic mycetoma) or true fungi" >fungi (eumycotic mycetoma). It usually involves the leg or foot (Madura foot), but the hand or any other site may be affected. There is swelling accompanied by formation of granulomas, suppurating abscesses, and multiple sinuses. Called also maduromycosis.my·ce·to·ma (mī'sē-tō'mă), A chronic infection involving the subcutaneous tissue, skin, and contiguous bone; characterized by the formation of localized lesions with tumefactions and multiple draining sinuses. The exudate contains granules that may be yellow, white, red, brown, or black, depending on the causative agent. Mycetoma is caused by two principal groups of microorganisms: 1) actinomycetoma is caused by actinomycetes, including species of Streptomyces, Actinomadurae, and Nocardia, 2) eumycetoma is caused by true fungi, including species of Madurella, Exophiala, Pseudallescheria, Curvularia, Neotestudina, Pyrenochaeta, Aspergillus, Leptosphaeria, Plemodomus, Polycytella, Fusarium, Phialophora, Corynespora, Cylindrocarpon, Pseudo-chaetosphaeronema, Bipolaris, and Acremonium. Synonym(s): Madura boil, Madura foot, maduromycosismy·ce·to·ma (mī'sĕ-tō'mă) 1. A chronic infection involving the feet characterized by the formation of localized lesions with tumefactions and multiple draining sinuses. The exudate contains granules that may be yellow, white, red, brown, or black, depending on the causative agent. Actinomycotic mycetoma is caused by bacterial species in the actinomycetes group; eumycotic mycetoma is caused by true fungi. Synonym(s): Madura boil, maduromycosis. 2. Any tumor with draining sinuses produced by filamentous fungi. Madura, a district in India where the condition was first described in 1842. Madura foot - infectious fungal disease localized predominantly in the foot, having discharge from the exposed area. Synonym(s): Ballingall disease; maduromycosismaduromycosis - Synonym(s): Madura foot |