Mustargen

Mustargen

 [mus´ter-jen] trademark for a preparation of mechlorethamine hydrochloride, an antineoplastic agent.

Mustargen

(mŭs′tər-jən) A trademark for the drug mechlorethamine hydrochloride.

mechlorethamine

A nitrogen mustard derivative which binds to DNA, crosslinking both strands to prevent its replication.
Global village
Mechlorethamine was first developed as a chemical weapon.
Oncology
A nitrogen mustard alkylating agent used for managing lymphomas; part of MOPP.
 
Adverse effects
Nausea, vomiting, marrow suppression, skin vesiculation at injection site.