mitoxantrone

[mi″to-zan´trōn] a DNA-reactive agent of the anthracenedione group that inserts into DNA, causing crosslinks and strand breaks; administered intravenously as the hydrochloride salt as an antitumor antibiotic for the treatment of leukemia" >acute myelogenous leukemia and advanced, hormone-refractory prostate cancer. It is also used to reduce the frequency and severity of relapses in patients with secondary multiple sclerosis.

mitoxantrone

Novantrone^® Oncology A synthetic antitumor antibiotic Indications Combined with steroids, for treating hormone-refractory prostate CA, breast CA, AML and other lymphoproliferative malignancy and multiple sclerosis Pharmacokinetics Similar to doxorubicin Side effects Dose-limiting granulocytopenia, thrombocytopenia, N&V

单词	mitoxantrone
释义	mitoxantrone mitoxantrone [mi″to-zan´trōn] a DNA-reactive agent of the anthracenedione group that inserts into DNA, causing crosslinks and strand breaks; administered intravenously as the hydrochloride salt as an antitumor antibiotic for the treatment of leukemia" >acute myelogenous leukemia and advanced, hormone-refractory prostate cancer. It is also used to reduce the frequency and severity of relapses in patients with secondary multiple sclerosis. mitoxantrone Novantrone^® Oncology A synthetic antitumor antibiotic Indications Combined with steroids, for treating hormone-refractory prostate CA, breast CA, AML and other lymphoproliferative malignancy and multiple sclerosis Pharmacokinetics Similar to doxorubicin Side effects Dose-limiting granulocytopenia, thrombocytopenia, N&V
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