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orexin
o·rex·in O5128250 (ô-rĕk′sĭn)n. Either of two neuropeptide hormones synthesized in the hypothalamus that regulate sleep and wakefulness and whose dysfunction causes narcolepsy. Also called hypocretin.
[Greek orexis, appetite (from the view that orexin stimulates appetite; see anorexia) + -in.]orexin (əˈrɛksɪn) na hormone that promotes wakefulness and stimulates the appetiteTranslationsorexin
orexin (ORX), (ō-rek'sin), Neuropeptide involved in neuroendocrine function including feeding and drinking behavior; two subtypes, A and B, exist.orexin (ô-rĕk′sĭn)n. Either of two neuropeptide hormones synthesized in the hypothalamus that regulate sleep and wakefulness and whose dysfunction causes narcolepsy. Also called hypocretin.o·rex·in (ōr-eks'in) A class of hypothalamic neuropeptide hormones that regulates sleep cycles and energy expenditure; they probably do not directly affect appetite, as was once believed. orexin One of a pair of centrally-acting neuropeptides produced by the lateral hypothalamus where the sensation of hunger is mediated. Rats given orexin will eat about ten times the normal amount of food and rats starved for 48 hours have more than twice the normal concentrations of orexin. There are also specific receptors for the two orexins. These facts are being exploited in the design of drugs that can both stimulate and reduce appetite. |