mixed lymphocyte culture reaction

mixed lym·pho·cyte cul·ture test

a test for histocompatibility of HLA-D antigens in which donor and recipient lymphocytes are mixed in culture; the degree of incompatibility is indicated by the number of cells that have undergone transformation and mitosis, or by the uptake of radioactive isotope-labeled thymidine. Synonym(s): MLC test

mixed lymphocyte culture reaction

A laboratory test in which lymphocytes from different individuals are mixed to identify the presence of particular HLA class II antigens. The T cells from the “responder” will synthesize DNA and proliferate only if they do not have the same histocompatibility antigens as the “donor cells, ” homozygous cells with known HLA types. The donor cells are irradiated to prevent their proliferation during the test.

单词	mixed lymphocyte culture reaction
释义	DictionarySeeMLC mixed lymphocyte culture reaction mixed lym·pho·cyte cul·ture test a test for histocompatibility of HLA-D antigens in which donor and recipient lymphocytes are mixed in culture; the degree of incompatibility is indicated by the number of cells that have undergone transformation and mitosis, or by the uptake of radioactive isotope-labeled thymidine. Synonym(s): MLC test mixed lymphocyte culture reaction A laboratory test in which lymphocytes from different individuals are mixed to identify the presence of particular HLA class II antigens. The T cells from the “responder” will synthesize DNA and proliferate only if they do not have the same histocompatibility antigens as the “donor cells, ” homozygous cells with known HLA types. The donor cells are irradiated to prevent their proliferation during the test. AcronymsSeeMLCR
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