non-Hodgkin's lymphoma

lymphoma, non-Hodgkin's,

any cancer of the lymphoid tissue (see lymphatic systemlymphatic system
, network of vessels carrying lymph, or tissue-cleansing fluid, from the tissues into the veins of the circulatory system. The lymphatic system functions along with the circulatory system in absorbing nutrients from the small intestines.
..... Click the link for more information. ) in which the Reed-Sternberg cells characteristic of Hodgkin's diseaseHodgkin's disease,
a type of cancer of the lymphatic system. First identified in 1832 in England by Thomas Hodgkin, it is a type of malignant lymphoma. Incidence peaks in young adults and the elderly.
..... Click the link for more information. (the other category of lymphoma) are not present. There are about 10 different types of non-Hodgkin's lymphomas, some slower- or faster-growing than others. Non-Hodgkin's lymphoma can affect children as well as adults. In most cases the cause is unknown, but an increased incidence has been observed in people who have been exposed to Agent OrangeAgent Orange,
herbicide used by U.S. forces during the Vietnam War to expose enemy guerrilla forces in forested areas. Agent Orange contains varying amounts of dioxin. Exposure to the defoliant has been linked with chemical acne, non-Hodgkin's lymphoma, Hodgkin's disease,
..... Click the link for more information. , and some forms of the disease are frequently seen in people with AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
..... Click the link for more information. , many of these in association with latent Epstein-Barr virus infection.

Symptoms

The first symptom of non-Hodgkin's lymphoma is often a painless swelling of a lymph node in the neck, the groin, or under the arm. Other symptoms include fever, night sweats, itching, and unexplained weight loss. Diagnosis is made by laboratory study of tissue obtained by taking a biopsybiopsy
, examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended.
..... Click the link for more information. of the suspicious lymph node or nodes.

Treatment

Treatment depends on how far the disease has progressed. It may include external-beam radiation therapy, chemotherapy, or biological therapy (boosting the body's immune response to the disease). Rituxan, a genetically engineered drug involving monoclonal antibodiesmonoclonal antibody,
an antibody that is mass produced in the laboratory from a single clone and that recognizes only one antigen. Monoclonal antibodies are typically made by fusing a normally short-lived, antibody-producing B cell (see immunity) to a fast-growing cell, such as
..... Click the link for more information. , has been approved for use against some low-grade (slow-growing) non-Hodgkin's lymphoma.

Bone marrowbone marrow,
soft tissue filling the spongy interiors of animal bones. Red marrow is the principal organ that forms blood cells in mammals, including humans (see blood). In children, the bones contain only red marrow.
..... Click the link for more information. transplantation is also sometimes used. In this technique, bone marrow (blood cell–producing tissue inside bone) is taken from the patient and treated to kill any cancer cells. The patient is then given very high dose chemotherapy designed to destroy the cancer; it also destroys the remaining bone marrow. After chemotherapy, the stored marrow is reinserted into the patient. In children, chemotherapy is the most common treatment.

Bibliography

See publications of the National Cancer Institute and the American Cancer Society.

Non-Hodgkin's lymphoma

non-Hodgkins' lymphoma

A lymphoid cancer that is not Hodgkins disease: NHL ALL, B cell lymphoma, Burkitt's lymphoma, diffuse cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, lymphoblastic lymphoma, mantle cell lymphoma, mycosis fungoides, post-transplantation lymphoproliferative disorder, small non-cleaved cell lymphoma, T-cell lymphoma Epidemiology Incidence ↑ 8.5/105 in 1973→15/105 in 1990 (21/105, in 2000, Canada ♂), ±53,900 new cases/yr, US in 2002; 60% of all lymphomas are NHLs, of which 55% are diffuse, 45% are nodular Risk factors AIDS, primary immunodeficiency, immunosuppression, transplants, exposure to pesticides, hair dyes, smoking, alcohol, in older ♀–linked to ↑ consumption of meat/animal fats– Management Chemotherapy, especially CHOP Complications Spinal cord compression occurs in up to 10%, which is often aggressive, and may respond to high-dose RT. See Lymphoma, REAL classification, Working Formulation. Non-Hodgkin's lymphoma Stage I CA present in only one lymph node area or in only one extranodal regional/organ Stage II CA present in ≥ 2 lymph node areas on same side of diaphragm; CA present in only one extranodal area or organ outside the lymph nodes and in the lymph nodes around it. Other lymph node areas on the same side of the diaphragm may also have cancer Stage III CA present in lymphoid tissue on both sides of the diaphragm; tumor may also have spread to an area or organ near the lymph node areas and/or to the spleen Stage IV CA has spread to > one organ or organs outside lymphoid tissue; CA has spread to only one organ outside the lymph system, but lymph nodes distant from that organ are involved

Non-Hodgkin's lymphoma

Cancer that originates in the lymphatic system and typically spreads throughout the body.Mentioned in: Beta 2 -Microglobulin Test

单词	non-hodgkin's lymphoma
释义	non-Hodgkin's lymphoma non-Hodg·kin lymphoma N5158000 (nŏn′hŏj′kĭn) or non-Hodg·kin's lymphoma (-kĭnz)n. Any of a large group of lymphomas that can be slow-growing or fast-growing, involve malignancies of either B cells or T cells, and are typically distinguished from Hodgkin lymphoma by the absence of Reed-Sternberg cells. Symptoms include enlarged lymph nodes, fever, night sweats, and weight loss. non-Hodgkin's lymphoma (-ˈhɒdʒkɪnz) n (Pathology) any form of lymphoma other than Hodgkin's disease non-Hodgkin's lymphoma n. any of several malignancies of the lymphatic system in which the cells characteristic of Hodgkin's disease are absent. [1975–80] non-Hodgkin's lymphoma lymphoma, non-Hodgkin's, any cancer of the lymphoid tissue (see lymphatic systemlymphatic system , network of vessels carrying lymph, or tissue-cleansing fluid, from the tissues into the veins of the circulatory system. The lymphatic system functions along with the circulatory system in absorbing nutrients from the small intestines. ..... Click the link for more information. ) in which the Reed-Sternberg cells characteristic of Hodgkin's diseaseHodgkin's disease, a type of cancer of the lymphatic system. First identified in 1832 in England by Thomas Hodgkin, it is a type of malignant lymphoma. Incidence peaks in young adults and the elderly. ..... Click the link for more information. (the other category of lymphoma) are not present. There are about 10 different types of non-Hodgkin's lymphomas, some slower- or faster-growing than others. Non-Hodgkin's lymphoma can affect children as well as adults. In most cases the cause is unknown, but an increased incidence has been observed in people who have been exposed to Agent OrangeAgent Orange, herbicide used by U.S. forces during the Vietnam War to expose enemy guerrilla forces in forested areas. Agent Orange contains varying amounts of dioxin. Exposure to the defoliant has been linked with chemical acne, non-Hodgkin's lymphoma, Hodgkin's disease, ..... Click the link for more information. , and some forms of the disease are frequently seen in people with AIDSAIDS or acquired immunodeficiency syndrome, fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981. ..... Click the link for more information. , many of these in association with latent Epstein-Barr virus infection. Symptoms The first symptom of non-Hodgkin's lymphoma is often a painless swelling of a lymph node in the neck, the groin, or under the arm. Other symptoms include fever, night sweats, itching, and unexplained weight loss. Diagnosis is made by laboratory study of tissue obtained by taking a biopsybiopsy , examination of cells or tissues removed from a living organism. Excised material may be studied in order to diagnose disease or to confirm findings of normality. Preparatory techniques depend on the nature of the tissue and the kind of study intended. ..... Click the link for more information. of the suspicious lymph node or nodes. Treatment Treatment depends on how far the disease has progressed. It may include external-beam radiation therapy, chemotherapy, or biological therapy (boosting the body's immune response to the disease). Rituxan, a genetically engineered drug involving monoclonal antibodiesmonoclonal antibody, an antibody that is mass produced in the laboratory from a single clone and that recognizes only one antigen. Monoclonal antibodies are typically made by fusing a normally short-lived, antibody-producing B cell (see immunity) to a fast-growing cell, such as ..... Click the link for more information. , has been approved for use against some low-grade (slow-growing) non-Hodgkin's lymphoma. Bone marrowbone marrow, soft tissue filling the spongy interiors of animal bones. Red marrow is the principal organ that forms blood cells in mammals, including humans (see blood). In children, the bones contain only red marrow. ..... Click the link for more information. transplantation is also sometimes used. In this technique, bone marrow (blood cell–producing tissue inside bone) is taken from the patient and treated to kill any cancer cells. The patient is then given very high dose chemotherapy designed to destroy the cancer; it also destroys the remaining bone marrow. After chemotherapy, the stored marrow is reinserted into the patient. In children, chemotherapy is the most common treatment. Bibliography See publications of the National Cancer Institute and the American Cancer Society. Non-Hodgkin's lymphoma non-Hodgkins' lymphoma A lymphoid cancer that is not Hodgkins disease: NHL ALL, B cell lymphoma, Burkitt's lymphoma, diffuse cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, lymphoblastic lymphoma, mantle cell lymphoma, mycosis fungoides, post-transplantation lymphoproliferative disorder, small non-cleaved cell lymphoma, T-cell lymphoma Epidemiology Incidence ↑ 8.5/105 in 1973→15/105 in 1990 (21/105, in 2000, Canada ♂), ±53,900 new cases/yr, US in 2002; 60% of all lymphomas are NHLs, of which 55% are diffuse, 45% are nodular Risk factors AIDS, primary immunodeficiency, immunosuppression, transplants, exposure to pesticides, hair dyes, smoking, alcohol, in older ♀–linked to ↑ consumption of meat/animal fats– Management Chemotherapy, especially CHOP Complications Spinal cord compression occurs in up to 10%, which is often aggressive, and may respond to high-dose RT. See Lymphoma, REAL classification, Working Formulation. Non-Hodgkin's lymphoma Stage I CA present in only one lymph node area or in only one extranodal regional/organ Stage II CA present in ≥ 2 lymph node areas on same side of diaphragm; CA present in only one extranodal area or organ outside the lymph nodes and in the lymph nodes around it. Other lymph node areas on the same side of the diaphragm may also have cancer Stage III CA present in lymphoid tissue on both sides of the diaphragm; tumor may also have spread to an area or organ near the lymph node areas and/or to the spleen Stage IV CA has spread to > one organ or organs outside lymphoid tissue; CA has spread to only one organ outside the lymph system, but lymph nodes distant from that organ are involved Non-Hodgkin's lymphoma Cancer that originates in the lymphatic system and typically spreads throughout the body.Mentioned in: Beta 2 -Microglobulin Test See NHL See NHLThesaurusSeelymphoma
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non-Hodgkin's lymphoma

non-Hodg·kin lymphoma

non-Hodgkin's lymphoma

non-Hodgkin's lymphoma

non-Hodgkin's lymphoma

lymphoma, non-Hodgkin's,

Symptoms

Treatment

Bibliography

Non-Hodgkin's lymphoma

non-Hodgkins' lymphoma

Non-Hodgkin's lymphoma