autoimmune lymphoproliferative syndrome
autoimmune lymphoproliferative syndrome
A condition caused by defective lymphocyte homeostasis and characterised by:• Non-malignant lymphoproliferation (lymphadenopathy, hepatosplenomegaly with or without hypersplenism) that often improves with age;
• Autoimmune disease, mostly directed toward peripheral blood cells; and
• Lifelong increased risk of Hodgkin and non-Hodgkin lymphoma.