law of Bergonie and Tribondeau


law of Ber·go·nié and Tri·bon·deau

(law bĕr-gō-nyē' trē-bon-dō') Concept in radiobiology used to relate ionizing radiation effectiveness on cells that are actively mitotic and undifferentiated and have a long mitotic cycle.

law of Bergonié and Tribondeau

A fundamental law of radiation biology that states that the radiosensitivity of a tissue is increased the greater the number of undifferentiated cells in the tissue, the greater the mitotic activity, and the greater the length of time that they are actively proliferating.See also: law