NEDD1

NEDD1

A gene on chromosome 12q23.1 that encodes a ubiquitin-like protein localised in centrosomes by way of WD40 repeats located in the amino-terminal.
Molecular pathology
NEDD1 depletion results in impaired centrosome and chromatin microtubule assembly due to failure of microtubule nucleation which compromises spindle formation.