microelectronic array

microelectronic array

A system used for molecular diagnostic genotyping that uses microelectrodes to concentrate DNA samples and accelerate probe hybrisation. Microelectronic arrays have been developed for DNA hybridisation analysis of point mutations, single nucleotide polymorphisms, short tandem repeats and gene expression. In addition to a variety of molecular biology and genomic research applications, such devices are also used for infectious disease detection, genetic and cancer diagnostics, and pharmacogenomic applications; they can be used to detect DNA, RNA, proteins, enzymes, antibodies and cells.