| 单词 | microencephaly |
| 释义 | microencephalymicroencephaly[¦mī·krō·en′sef·ə·lē]microencephalymi·cren·ceph·a·ly(mī'kren-sef'ă-lē),microcephalyAn abnormally small head, which is usually associated with neurodevelopmental delay and mental retardation. A standard definition is any brain or head which is ≥ 3 standard deviations below the mean for a person’s age, sex, height, weight and race.Conditions associated with microcephaly Cockayne, Miller-Dieker, Smith-Lemli-Opitz, Rothmund-Thomson, and Wolf-Hirschhorn syndromes; chromosomal defects (cat-cry or 5p- and trisomy 13 syndromes), in utero infection (CMV), rubella, toxoplasmosis, toxic exposure (foetal alcohol and foetal hydantoin syndromes), radiation (the only confirmed congenital defect specifically linked to atomic bomb blasts (i.e., in Hiroshima and Nagasaki)), or trauma. Genes linked to microcephaly ASPM, CDK5RAP2, CENPJ, MCPH1, MCPH2, MCPH4. mi·cren·ceph·a·ly(mī'kren-sef'ă-lē)Synonym(s): microencephaly. |
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