myocardial depressant factor


my·o·car·di·al de·pres·sant fac·tor (MDF),

a toxic factor in shock that impairs cardiac contractility; probably a peptide released with underperfusion of the splanchnic area at the release of proteolytic enzymes from the pancreas.

myocardial depressant factor

Uncertain; a substance allegedly present in the circulation that was once thought to be responsible for a suboptimal cardiac response to burns, shock and other stressing conditions (e.g.,accumulations of lactic acid and other stressants).

my·o·car·di·al de·pres·sant fac·tor

(MDF) (mī'ō-kahr'dē-ăl dĕ-pres'ănt fak'tŏr) A toxic factor in shock that impairs cardiac contractility.